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Explainer / What is ‘Ozempic face’ and how can you avoid it? Hollywood’s miracle diet ‘pill’ used by Amy Schumer, Sharon Osbourne and Elon Musk results in a sunken face – but fillers can help counteract it

Reality TV star Scott Disick’s post-Ozempic transformation resulted in a gaunt-looking face – and he’s not the only one who has it. Photos: @letthelordbewithyou/Instagram

Ozempic has taken Hollywood by storm.

Originally made by Danish pharmaceutical company Novo Nordisk as a prescription drug for adult patients with type 2 diabetes, Ozempic is now the latest miracle diet “pill”.

Anti-diabetic medication Ozempic, made by Danish pharmaceutical company Novo Nordisk. Photo: TNS

Known generically as semaglutide, Ozempic is a drug that works to treat type 2 diabetic patients by mimicking a hormone in the body that helps the pancreas increase insulin production, effectively lowering high blood sugar levels. It also slows down digestion and induces satiety resulting in suppressed appetites and weight loss.

Several celebrities like Khloé Kardashian and Jessica Simpson have been accused of using the medication – but denied it – while a few have even spoken out about their disapproval towards using Ozempic for weight loss.

Uncut Gems star Julia Fox told Entertainment Tonight last year that she would never take the drug as “there are diabetics that need it”.

Julia Fox is critical of using Ozempic for weight loss. Photo: GC Images

However, several high-profile celebrities, such as Amy Schumer and Elon Musk, have openly admitted to taking the drug and successfully shedding pounds. Musk even credited his “fit, ripped and healthy” body to Novo Nordisk’s Wegovy, a higher dose of semaglitude.

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Unfortunately, drugs like Ozempic and Wegovy come with side effects such as nausea and excessive weight loss. British television personality Sharon Osbourne, who used Ozempic for weight loss, told British media last year, “You can lose so much weight and it’s easy to become addicted to that, which is very dangerous.”

Sharon Osbourne has spoken out against Ozempic due to her own bad experience. Photo: @sharonosbourne/Instagram

“I couldn’t stop losing weight and now I’ve lost 42lbs – and I can’t afford to lose any more,” she said.

What does Ozempic do to your face?

Reality TV star Scott Disick lost so much weight using Ozempic that his face looked gaunt. Photo: @letthelordbewithyou/Instagram

Reality TV star Scott Disick’s post-Ozempic transformation was so shocking that several fans expressed concern for his health over his extreme weight loss. According to British media, the 40-year-old is now seeking help and working with nutritionists to get back on track.

The medicine can also lead to users looking gaunt. Dr Paul Jarrod Frank, a celebrity dermatologist from New York, coined the term “Ozempic face” when he observed noticeable changes in the facial appearance of several patients who had lost weight while using the medication.

The side effect has been dubbed “Ozempic face” on social media. Photo: Reuters
The side effect can be characterised by “increased signs of ageing, loss of fat, which can lead the skin to become loose and sag, and a hollowed-out appearance”, according to Medical News Today.

Luckily, Galderma Group AG’s boss has an answer for people suffering from sunken faces: fillers.

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Can fillers really fix Ozempic Face?

Fillers can be used to avoid “Ozempic face”. Photo: Getty Images
Galderma’s Sculptra skin treatment and other fillers “should be able to restore this”, CEO Flemming Ornskov said in an interview following its first-quarter earnings.

“I think that will be another growth wave in that space, which I will make sure to capture,” he added.

Sculptra skin treatment and other fillers can restore sunken faces. Photo: West End Plastic Surgery
Weight-loss drugs produced by Novo and Eli Lilly & Co. have surged in popularity as people rush to find quicker and easier ways of shedding pounds. But many patients “end up with faces that look sunk”, Ornskov said. Sculptra boosts collagen production, which helps to treat wrinkles and other signs of ageing.

Ornskov was speaking as the company reported its first earnings as a public company. Galderma, whose brands also include Cetaphil and Alastin, saw sales rise 12 per cent to US$1.07 billion in the first quarter.

Pharmaceutical company Galderma manufactures fillers. Photo: American Board of Facial Cosmetics

Galderma’s shares have surged since last month’s listing, making it one of the most successful initial public offerings of the year amid the recent drought in capital markets.

Beauty
  • Celeb dermatologist Dr Paul Jarrod Frank coined the term ‘Ozempic face’ when he observed noticeable changes in the appearance of several patients who had lost weight using Ozempic
  • The drug can cause signs of ageing, loss of fat and loose, sagging skin, but pharmaceutical companies are making bank manufacturing fillers to combat this, such as the collagen-boosting treatment Sculptra